Yang Claire Yang, Courtney Boen, Karen Gerken, Ting Li, Kristen Schorpp, and Kathleen Mullan Harris, ‘Social relationships and physiological determinants of longevity across the human life span’, http://www.pnas.org/content/early/2016/01/02/1511085112.abstract, PNAS Online (July 20, 2015).

Social integration

We found that a higher degree of social integration was associated with a lower risk of physiological dysregulation in a dose response manner both early and later life. Conversely, lack of social connections was associated with a significantly increased risk of certain life stages. (…) Physiological effects of structural and functional aspects of social relationships occur uniquely in adolescence and midlife and continue into old age.